Lawrence James "Larry" DeLucas (O. D., Ph.D.) is an American biochemist who flew aboard NASA Space Shuttle mission STS-50 as a Payload Specialist. DeLucas was a member of the crew of Space Shuttle Columbia for STS-50 (June 25-July 9, 1992), the United States Microgravity Laboratory-1 (USML-1) Spacelab mission. Over a two-week period, the crew conducted a wide variety of experiments relating to materials processing and fluid physics. At mission conclusion, DeLucas had traveled over 5.7 million miles in 221 Earth orbits, and had logged over 331 hours in space.